Chemical Structure : ELN484228
CAS No.: 312-63-0
货号: PC-63274Not For Human Use, Lab Use Only.
ELN484228 is a small molecule binder of α-synuclein that shows protective effect in cellular models of αSyn-mediated vesicular dysfunction.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | ¥880 | In stock | |
50 mg | ¥1580 | In stock | |
100 mg | ¥2580 | In stock | |
250 mg | Get quote | ||
1 g | Get quote |
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ELN484228 is a small molecule binder of α-synuclein that shows protective effect in cellular models of αSyn-mediated vesicular dysfunction.
ELN484228 rescues α-synuclein-induced disruption of vesicle trafficking and dopaminergic neuronal loss and neurite retraction most likely by reducing the amount of α-synuclein targeted to sites of vesicle mobilization such as the synapse in neurons or the site of bead engulfment in microglial cells.
ELN484228 shows potential therapeutic strategy for Parkinson's disease.
分子量 | 251.28 | |
分子式 | C12H10FNO2S | |
外观性状 | Solid | |
储存条件 |
|
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
N-(4-Fluorophenyl)-benzenesulfonamide |
1. Tóth G, et al. PLoS One. 2014 Feb 14;9(2):e87133.
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