Chemical Structure : EGCG
CAS No.: 989-51-5
货号: PC-21095Not For Human Use, Lab Use Only.
EGCG (Epigallocatechin-3-gallate) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis, inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 mg | ¥350 | In stock | |
100 mg | ¥550 | In stock | |
250 mg | ¥950 | In stock | |
1 g | Get quote |
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EGCG (Epigallocatechin-3-gallate) is a major polyphenol in green tea, which can inhibit cell proliferation and induce cell apoptosis, inhibits glutamate dehydrogenase 1/2 (GDH1/2, GLUD1/2) activity.
EGCG reduces D-2-HG production in HCT116-IDH1 wt/R132H cells, decreases proliferation rates of IDH1 mut cells and at high doses sensitized cancer cells to ionizing radiation.
EGCG has a potent anticancer, antioxidant and anti-inflammatory properties against various types of cancers such as colorectal cancer, myeloid leukemia, thyroid carcinoma.
分子量 | 458.38 | |
分子式 | C22H18O11 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(2R,3R)-5,7-dihydroxy-2-(3,4,5-trihydroxyphenyl)chroman-3-yl] 3,4,5-trihydroxybenzoate |
1. De Amicis F, et al. J Cell Physiol. 2013.
2. Peeters TH, et al. Cancer Metab. 2019 May 20;7:4.
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