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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-EDV33
EDV33

Chemical Structure : EDV33

CAS No.: 3034671-41-2

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EDV33

货号: PC-22948Not For Human Use, Lab Use Only.

EDV33 is a potent, non-selective inhibitor of ADAMTSs with Ki app value of 68, 31, 6.5, 4.3 and 4.0 nM for ADAMTS-7, ADAMTS-4, ADAMTS-5, ADAM-17 and MMP-2 respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

EDV33 is a potent, non-selective inhibitor of ADAMTSs with Ki app value of 68, 31, 6.5, 4.3 and 4.0 nM for ADAMTS-7, ADAMTS-4, ADAMTS-5, ADAM-17 and MMP-2 respectively.

物理化学性质&存储条件

分子量 550.00
分子式 C25H25ClFN3O6S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(R)-N-(4-((4-((2-chloro-4-fluorobenzyl)oxy)phenyl)sulfonamido)-5-(hydroxyamino)-5-oxopentyl)benzamide

参考文献

1. Salvatore Santamaria, et al. J Enzyme Inhib Med Chem. 2021 Dec;36(1):2160-2169.

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