Zelicapavir (EDP-938) | RSV N protein inhibitor | Probechem Biochemicals

Chemical Structure : EDP-938

CAS No.: 2070852-76-3

加入收藏

EDP-938 (Zelicapavir, EDP938)

货号: PC-23057Not For Human Use, Lab Use Only.

Zelicapavir (EDP-938) is a potent RSV viral nucleoprotein (N) inhibitor of both RSV-A and RSV-B activity, inhibits RSV induced CPE with EC50 of 52 nM in HEp-2 cells.

规格	价格	库存
2 mg	￥2980	In stock
5 mg	￥4980	In stock
10 mg	￥7280	In stock
25 mg		Get quote
100 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

Zelicapavir (EDP-938) is a potent RSV viral nucleoprotein (N) inhibitor of both RSV-A and RSV-B activity, inhibits RSV induced CPE with EC50 of 52 nM in HEp-2 cells.
Zelicapavir (EDP-938) is highly active against all RSV-A and B laboratory strains and clinical isolates tested in vitro in various cell lines and assays, with EC50 of 21, 23 and 64 nM against Long (A), M37 (A) and VR-955 (B) strains, respectively, in the primary human bronchial epithelial cells (HBECs).
Zelicapavir (EDP-938) effectively blocks RSV replication by targeting a post-entry replication stage of the viral life cycle.

物理化学性质&存储条件

分子量	549.51
分子式	C27H22F3N7O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	2H-1,4-Benzodiazepin-2-one, 1,3-dihydro-3-[[5-[3-(4-morpholinyl)-5-(trifluoromethyl)-2-pyridinyl]-1,3,4-oxadiazol-2-yl]amino]-5-phenyl-, (3S)-

参考文献

1. Rhodin MHJ, et al. PLoS Pathog. 2021 Mar 15;17(3):e1009428.

2. Ahmad A, et al. N Engl J Med. 2022 Feb 17;386(7):655-666.

3. Patent WO2017015449.

EDP-938 (Zelicapavir, EDP938)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

EDP-938 (Zelicapavir, EDP938)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.