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首页-小分子抑制剂&激动剂-Others-Other Targets-EC5026
EC5026

Chemical Structure : EC5026

CAS No.: 1809885-32-2

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EC5026 (EC 5026, BPN-19186)

货号: PC-21825Not For Human Use, Lab Use Only.

EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain.

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5 mg ￥780 In stock
10 mg ￥1180 In stock
25 mg ￥1880 In stock
50 mg ￥2880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

EC5026 (BPN-19186) is a potent, selective orally active soluble epoxide hydrolase (sEH) inhibitor with IC50 of 0.04 nM, shows potential for the treatment of neuropathic pain.

物理化学性质&存储条件

分子量 405.39
分子式 C18H23F4N3O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(S)-1-(3-Fluoro-4-(trifluoromethoxy)phenyl)-3-(1-(2-methylbutanoyl)piperidin-4-yl)urea

参考文献

1. Abigail G Kelly, et al. Proc Natl Acad Sci U S A. 2024 Feb 13;121(7):e2314085121.

2. Hammock BD, et al. J Med Chem. 2021 Feb 25;64(4):1856-1872.

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