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首页-小分子抑制剂&激动剂-GPCR-Neurokinin Receptor-EB1002
EB1002

Chemical Structure : EB1002

CAS No.: 2770688-48-5

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EB1002 (EB-1002)

货号: PC-23421Not For Human Use, Lab Use Only.

EB1002 is a potent, selective, long-acting neurokinin 2 receptor (NK2R) agonist, enhances insulin sensitization.

规格 价格 库存 数量
5 mg ￥2180 In stock
10 mg ￥3580 In stock
25 mg ￥5580 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

EB1002 is a potent, selective, long-acting neurokinin 2 receptor (NK2R) agonist, enhances insulin sensitization.
EB1002 is highly selective against NK1R on both mouse tachykinin receptors and human tachykinin receptors.
EB1002 significantly decreases body weight, blood glucose, triglycerides and cholesterol, and ameliorates insulin resistance.

物理化学性质&存储条件

分子量 1537.86
分子式 C73H124N12O23
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S,25S)-2-(((5S,8S,14S,17S,20S)-24-amino-5-carbamoyl-17-(4-hydroxybenzyl)-8-isobutyl-14-isopropyl-9-methyl-7,10,13,16,19-pentaoxo-2-oxa-6,9,12,15,18-pentaazatetracosan-20-yl)carbamoyl)-4,13,22,27-tetraoxo-6,9,15,18-tetraoxa-3,12,21,26-tetraazatritetracontane-1,25,43-tricarboxylic acid

参考文献

1. Sass F, et al. Nature. 2024 Nov 13. doi: 10.1038/s41586-024-08207-0.

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