EAI001 | mutant EGFR inhibitor | Probechem Biochemicals

Chemical Structure : EAI001

CAS No.: 892772-75-7

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货号: PC-21850Not For Human Use, Lab Use Only.

EAI001 is a potent, mutant-selectiveepidermal growth factor receptor (EGFR) allosteric inhibitor with IC50 value of 24 nM for EGFRL858R/T790M.

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EAI001 is a potent, mutant-selectiveepidermal growth factor receptor (EGFR) allosteric inhibitor with IC50 value of 24 nM for EGFRL858R/T790M.

分子量	349.41
分子式	C19H15N3O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(3-oxo-1H-isoindol-2-yl)-2-phenyl-N-(1,3-thiazol-2-yl)acetamide

1. Maity S, et al. Pharmacol Rep. 2020 Aug;72(4):799-813.