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首页-小分子抑制剂&激动剂-Immunology/Inflammation-Toll-like Receptor (TLR)-E104
E104

Chemical Structure : E104

CAS No.: 1610431-21-4

E104 (TLR7 agonist E014)

货号: PC-21155Not For Human Use, Lab Use Only.

E014 is a potent, selective TLR7 agonist with EC50 of 69 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

E014 is a potent, selective TLR7 agonist with EC50 of 69 nM in Ramos Blue reporter assays, >500-fold selective for TLR7 over TLR8.

物理化学性质&存储条件

分子量 345.45
分子式 C21H23N5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-aminobenzyl)-2-butyl-1H-imidazo[4,5-c]quinolin-4-amine

参考文献

1. Emma G. DeYoung, et al. ACS Medicinal Chemistry Letters 2023

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