E-2212 | γ-secretase modulator | Probechem Biochemicals

Chemical Structure : E-2212

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货号: PC-22497Not For Human Use, Lab Use Only.

E-2212 is a potent, selective γ-secretase modulator with Aβ42 IC50 of 7 nM.

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E-2212 is a potent, selective γ-secretase modulator with Aβ42 IC50 of 7 nM.

分子量	480.50
分子式	C25H23F3N6O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(S,E)-2-(2-(6-methoxy-5-(4-methyl-1H-imidazol-1-yl)pyridin-2-yl)vinyl)-8-(2-(trifluoromethyl)phenyl)-5,6,7,8-tetrahydro-[1,2,4]triazolo[1,5-a]pyridine

1. Pettersson M, et al. J Med Chem. 2024 Jun 7. doi: 10.1021/acs.jmedchem.4c00580.