Chemical Structure : E-2012
CAS No.: 870843-42-8
货号: PC-42071Not For Human Use, Lab Use Only.
E-2012 (E2012) is a potent, second-generation γ-secretase modulator that decreases Aβ(1-39), Aβ(1-40) and A(1-42), and increases Aβ(1-37).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥1180 | In stock | |
10 mg | ¥1780 | In stock | |
25 mg | ¥2980 | In stock | |
50 mg | ¥4880 | In stock | |
100 mg | Get quote |
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E-2012 (E2012) is a potent, second-generation γ-secretase modulator that decreases Aβ(1-39), Aβ(1-40) and A(1-42), and increases Aβ(1-37).
分子量 | 419.4912 | |
分子式 | C25H26FN3O2 | |
外观性状 | Solid | |
储存条件 |
|
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Solubility |
10 mM in DMSO |
|
Chemical Name/SMILES |
2-Piperidinone, 1-[(1S)-1-(4-fluorophenyl)ethyl]-3-[[3-methoxy-4-(4-methyl-1H-imidazol-1-yl)phenyl]methylene]-, (3E)- |
1. Portelius E, et al. J Alzheimers Dis. 2010;21(3):1005-12.
2. Borgegard T, et al. J Biol Chem. 2012 Apr 6;287(15):11810-9.
3. Borghys H, et al. J Alzheimers Dis. 2012;28(4):809-22.
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