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Dual PI3K/BET 18DS

Chemical Structure : Dual PI3K/BET 18DS

CAS No.: 2750361-19-2

Dual PI3K/BET 18DS

货号: PC-21267Not For Human Use, Lab Use Only.

Dual PI3K/BET 18DS is a potent, chimeric dual PI3K/BET bromodomain inhibitor, demonstrates high selectivity, nanomolar range cellular potency, and compelling in vivo efficacy.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Dual PI3K/BET 18DS is a potent, chimeric dual PI3K/BET bromodomain inhibitor, demonstrates high selectivity, nanomolar range cellular potency, and compelling in vivo efficacy.

物理化学性质&存储条件

分子量 617.71
分子式 C34H35N9O3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-N-(4-(1-acetyl-2-methyl-1,2,3,4-tetrahydroquinolin-6-yl)benzyl)-6-(2-aminopyrimidin-5-yl)-8-morpholinoimidazo[1,2-a]pyrazine-2-carboxamide

参考文献

1. Danielle H Oh, et al. Proc Natl Acad Sci U S A. 2023 Sep 5;120(36):e2306414120.

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