Dual FXR-LIFR modulator 3a

Chemical Structure : Dual FXR-LIFR modulator 3a

加入收藏

货号: PC-23132Not For Human Use, Lab Use Only.

Dual FXR-LIFR modulator 3a is a first-in-class hybrid leukemia inhibitory factor receptor (LIFR) inhibitor and Farnesoid X receptor (FXR) agonist with IC50 of 2.0 uM and EC50 of 3.2 uM respectively, protects against the development of acute liver fibrosis and inflammation.

规格	价格	库存	数量
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

物理化学性质&存储条件

分子量	454.30
分子式	C24H17Cl2NO4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4'-((3-(2,6-dichlorophenyl)-5-methylisoxazol-4-yl)methoxy)-[1,1'-biphenyl]-3-carboxylic acid

参考文献

1. Rapacciuolo P, et al. J Med Chem. 2024 Oct 9. doi: 10.1021/acs.jmedchem.4c01651.