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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-GABA Receptor-Droperidol
Droperidol

Chemical Structure : Droperidol

CAS No.: 548-73-2

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Droperidol (Dehydrobenzperidol)

货号: PC-24815Not For Human Use, Lab Use Only.

Droperidol (Dehydrobenzperidol) is a butyrophenone pamine-2 receptor antagonist, inhibits the activation of GABA(A) and neuronal nicotinic receptors (nAChR) with IC50 of 12.6 nM and 5.8 μM, also specifically inhibits YTHDF2 and prevents associations of YTHDF2 with DDX1 and eIF3F.

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50 mg ￥480 In stock
100 mg ￥780 In stock
250 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Droperidol (Dehydrobenzperidol) is a butyrophenone pamine-2 receptor antagonist, inhibits the activation of GABA(A) and neuronal nicotinic receptors (nAChR) with IC50 of 12.6 nM and 5.8 μM, also specifically inhibits YTHDF2 and prevents associations of YTHDF2 with DDX1 and eIF3F.

物理化学性质&存储条件

分子量 379.44
分子式 C22H22FN3O2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(1-(4-(4-Fluorophenyl)-4-oxobutyl)-1,2,3,6-tetrahydropyridin-4-yl)-1H-benzo[d]imidazol-2(3H)-one

参考文献

1. Liu T, et al. Mol Cell. 2025 May 28:S1097-2765(25)00454-X.

2. Pamela Flood, et al. Anesthesiology. 2002 Apr;96(4):987-93.

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