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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Matrix Metalloproteinase (MMP)-Doxycycline
Doxycycline

Chemical Structure : Doxycycline

CAS No.: 564-25-0

Doxycycline

货号: PC-23168Not For Human Use, Lab Use Only.

Doxycycline is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, also is the orthoflaviviral NS2B-NS3 protease inhibitor, shows antiviral and anti-cancer cell proliferation activities.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Doxycycline is an orally active and broad-spectrum metalloproteinase (MMP) inhibitor, also is the orthoflaviviral NS2B-NS3 protease inhibitor, shows antiviral and anti-cancer cell proliferation activities.

物理化学性质&存储条件

分子量 444.44
分子式 C22H24N2O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(4S,4aR,5S,5aR,6R,12aS)-4-(Dimethylamino)-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxo-1,4,4a,5,5a,6,11,12a-octahydrotetracene-2-carboxamide

参考文献

1. Eusebio Manchado, et al. Nature. 2016 Jun 30;534(7609):647-51.

2. Chong Teoh T., et al. Molecules. 2021;26:4321.

3. Le Zhang, et al. Cell Cycle. 2017 Apr 18;16(8):737-745.

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