欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Glucokinase-Dorzagliatin
Dorzagliatin

Chemical Structure : Dorzagliatin

CAS No.: 1191995-00-2

加入收藏

Dorzagliatin (HMS-5552, HMS5552)

货号: PC-60040Not For Human Use, Lab Use Only.

Dorzagliatin (HMS-5552, HMS5552) is a novel potent, fourth-generation glucokinase (GK) activator.

规格 价格 库存 数量
2 mg (Free Sample) ￥280 In stock
10 mg ￥1280 In stock
25 mg ￥2280 In stock
50 mg ￥3880 In stock
100 mg Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Dorzagliatin (HMS-5552, HMS5552) is a novel potent, fourth-generation glucokinase (GK) activator.
HMS-5552 exerts its antidiabetic effect by inhibiting insulin resistance and increasing insulin sensitivity, significantly increased GK expression.
HMS-5552 effectively improves GK activity and insulin resistance by targeting both the liver and pancreas in rat T2DM models.

物理化学性质&存储条件

分子量 462.931
分子式 C22H27ClN4O5
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(2S)-2-[4-(2-chlorophenoxy)-2-oxo-2,5-dihydro-1H-pyrrol-1-yl]-N-{1-[(2R)-2,3-dihydroxypropyl]-1H-pyrazol-3-yl}-4-methylpentanamide

参考文献

1. Wang P, et al. J Diabetes Res. 2017;2017:5812607.

2. Xu H, et al. Drug Des Devel Ther. 2016 May 9;10:1619-26.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: