AA 861 (Docebenone) | 5-Lipoxygenase inhibitor | Probechem Biochemicals

Chemical Structure : Docebenone

CAS No.: 80809-81-0

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Docebenone (AA861, AA 861)

货号: PC-62455Not For Human Use, Lab Use Only.

AA 861 (Docebenone) is a potent, selective 5-Lipoxygenase (5-LO) inhibitor with IC50 of 0.8 uM.

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5 mg	￥2880	In stock
10 mg	￥4580	In stock
25 mg	￥7580	In stock
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100 mg		Get quote

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生物&药学活性

AA 861 (Docebenone) is a potent, selective 5-Lipoxygenase (5-LO) inhibitor with IC50 of 0.8 uM.
AA 861 (Docebenone) induces cytotoxic and anti-proliferative effects in 5-LO-positive Capan-2 pancreatic cancer cells.
AA 861 (Docebenone) also efficiently inhibits biofilms by preventing the formation of amyloid-like fibers.

物理化学性质&存储条件

分子量	326.436
分子式	C21H26O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	2-(12-hydroxydodeca-5,10-diynyl)- 3,5,6-trimethyl-p-benzoquinone

参考文献

1. Romero D, et al. Chem Biol. 2013 Jan 24;20(1):102-10.

2. Yoshimoto T, et al. Biochim Biophys Acta. 1982 Nov 12;713(2):470-3.

3. Fischer AS, et al. Br J Pharmacol. 2010 Oct;161(4):936-49.

Docebenone (AA861, AA 861)

生物&药学活性

物理化学性质&存储条件

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Docebenone (AA861, AA 861)

生物&药学活性

物理化学性质&存储条件

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