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Divin

Chemical Structure : Divin

CAS No.: 1443321-11-6

Divin (Iron chelator)

货号: PC-60169Not For Human Use, Lab Use Only.

Divin is a potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Divin is a potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells.
    Divin also is a small molecule inhibitor of bacterial divisome assembly.
    Divin downregulates the transcription of genes encoding proteins involved in cell division, reduce protein biosynthesis, and affects the spatiotemporal localization of the division machinery.

    物理化学性质&存储条件

    分子量 372.428
    分子式 C22H20N4O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    (E)-N'-((2-hydroxynaphthalen-1-yl)methylene)-3-(2-methyl-1H-benzo[d]imidazol-1-yl)propanehydrazide

    参考文献

    1. Santos TMA, et al. ACS Chem Biol. 2017 Dec 11. doi: 10.1021/acschembio.7b00560.

    2. Eun YJ, et al. J Am Chem Soc. 2013 Jul 3;135(26):9768-76.

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