Chemical Structure : Divin
货号: PC-60169Not For Human Use, Lab Use Only.
Divin is a potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells.
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Divin is a potent chelator of iron that arrests late stages of cytokinesis by blocking the physical process of constriction in dividing cells.
Divin also is a small molecule inhibitor of bacterial divisome assembly.
Divin downregulates the transcription of genes encoding proteins involved in cell division, reduce protein biosynthesis, and affects the spatiotemporal localization of the division machinery.
分子量 | 372.428 | |
分子式 | C22H20N4O2 | |
外观性状 | Solid | |
储存条件 |
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Solubility |
10 mM in DMSO |
1. Santos TMA, et al. ACS Chem Biol. 2017 Dec 11. doi: 10.1021/acschembio.7b00560.
2. Eun YJ, et al. J Am Chem Soc. 2013 Jul 3;135(26):9768-76.
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