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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-NADPH Oxidase (NOX)-Diphenyleneiodonium chloride
Diphenyleneiodonium chloride

Chemical Structure : Diphenyleneiodonium chloride

CAS No.: 4673-26-1

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Diphenyleneiodonium chloride (DPI)

货号: PC-72722Not For Human Use, Lab Use Only.

Diphenyleneiodonium chloride (DPI) is an inhibitor of NADPH oxidase and potent, irreversible iNOS/eNOS inhibitor, also is an agonist of GPR3 with weak or no cross-reactivity with other GPCRs.

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100 mg ￥4980 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Diphenyleneiodonium chloride (DPI) is an inhibitor of NADPH oxidase and potent, irreversible iNOS/eNOS inhibitor, also is an agonist of GPR3 (EC50=1 uM) with weak or no cross-reactivity with other GPCRs.

物理化学性质&存储条件

分子量 314.55
分子式 C12H8ClI
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

[1,1'-Biphenyl]-2,2'-diyliodonium chloride

参考文献

1. Chenli Ye, et al. J Pharmacol Exp Ther. 2014 Jun;349(3):437-43.

2. Ma W, et al. Nat Commun. 2022 Jan 26;13(1):529.

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