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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Calcium Channel -Diltiazem hydrochloride
Diltiazem hydrochloride

Chemical Structure : Diltiazem hydrochloride

CAS No.: 33286-22-5

Diltiazem hydrochloride (CRD-401)

货号: PC-44015Not For Human Use, Lab Use Only.

A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores.

规格 价格 库存 数量
5 g ¥880 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A postsynaptic muscle relaxant that inhibits Ca2+ ions release from sarcoplasmic reticulum stores; antagonizes ryanodine receptors; can prevent cell death in neural progenitor cells derived from Wolfram syndrome iPS cells.

Hypertension

Approved

物理化学性质&存储条件

分子量 450.9788
分子式 C22H27ClN2O4S
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,5-Benzothiazepin-4(5H)-one, 3-(acetyloxy)-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-, hydrochloride (1:1), (2S,3S)-

参考文献

1. Lu S, et al. Proc Natl Acad Sci U S A. 2014 Dec 9;111(49):E5292-301.

2. Zucchi R, et al. Pharmacol Rev. 1997 Mar;49(1):1-51.

3. Krause T, et al. Anaesthesia. 2004 Apr;59(4):364-73.

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