Chemical Structure : Dihydroberberine
CAS No.: 483-15-8
货号: PC-27255Not For Human Use, Lab Use Only.
Dihydroberberine (dhBBR) is a berberine derivative that inhibit mitochondrial respiratory complex I, improves whole-body insulin sensitivity through increased AMPK activity, exhibits synergistic effects with sunitinib on NSCLC NCI-H460 cells by repressing MAP kinase pathways.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 10 mg | ¥880 | In stock | |
| 25 mg | ¥1280 | In stock | |
| 50 mg | ¥1980 | In stock | |
| 100 mg | ¥3280 | In stock | |
| 250 mg | Get quote |
大包装,大折扣!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Dihydroberberine (dhBBR) is a berberine derivative that inhibit mitochondrial respiratory complex I, improves whole-body insulin sensitivity through increased AMPK activity, exhibits synergistic effects with sunitinib on NSCLC NCI-H460 cells by repressing MAP kinase pathways.
| 分子量 | 337.38 | |
| 分子式 | C20H19NO4 | |
| 外观性状 | Solid | |
| 储存条件 |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
9,10-Dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline |
|
1. Turner N, et al. Diabetes. 2008 May;57(5):1414-8.
2. Liu DL, et al. Chin J Integr Med. 2015 Feb;21(2):132-8.
3. Xu L, et al. Front Pharmacol. 2021 Apr 20;12:645879.
4. Dai B, et al. J Cell Mol Med. 2017 Oct;21(10):2573-2585.
备案号:沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright