Difamilast | PDE4B inhibitor | Probechem Biochemicals

Chemical Structure : Difamilast

CAS No.: 937782-05-3

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货号: PC-61372Not For Human Use, Lab Use Only.

Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).

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Difamilast (OPA-15406) is a novel potent, selective phosphodiesterase IV (PDE4) inhibitor with preference for PDE4B (IC50=11.2 nM).

分子量	446.451
分子式	3H24F2N2O5
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-({2-[4-(difluoromethoxy)-3-(propan-2-yloxy)phenyl]-1,3-oxazol-4-yl}methyl)-2-ethoxybenzamide

1. Hanifin JM, et al. J Am Acad Dermatol. 2016 Aug;75(2):297-305.