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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-Calcium Channel -Dicoumarol
Dicoumarol

Chemical Structure : Dicoumarol

CAS No.: 66-76-2

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Dicoumarol (Dicumarol)

货号: PC-23295Not For Human Use, Lab Use Only.

Dicoumarol (Dicumarol) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50 of 0.37 and 19.42 uM respectively, also is a potent VRAC inhibitor.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Dicoumarol (Dicumarol) is an inhibitor of both NAD(P)H:quinone oxidoreductase 1 (NQO1) and PDK1 with IC50 of 0.37 and 19.42 uM respectively, also is a potent VRAC inhibitor.

物理化学性质&存储条件

分子量 336.30
分子式 C19H12O6
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

3,3'-Methylenebis(4-hydroxy-2H-chromen-2-one)

参考文献

1. Chu J, et al. bioRxiv [Preprint]. 2023 Jan 8:2023.01.08.523161.

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