Diclofensine hydrochloride |CAS:34041-84-4 Probechem Biochemicals

Chemical Structure : Diclofensine hydrochloride

CAS No.: 34041-84-4

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Diclofensine hydrochloride (Ro 8-4650 hydrochloride)

货号: PC-45480Not For Human Use, Lab Use Only.

Diclofensine (Ro 8-4650) hydrochloride is an antidepressant that acts as a triple monoamine reuptake inhibitor.

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10 mg	￥1280	In stock
25 mg	￥2180	In stock
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生物&药学活性

Diclofensine (Ro 8-4650) hydrochloride is an antidepressant that acts as a triple monoamine reuptake inhibitor.
Diclofensine blocks the uptake of dopamine, noradrenaline, and serotonin by rat brain synaptosomes with IC50 of 0.74, 2.3, and 3.7 nM, respectively.
Diclofensine increases locomotor activity, decreases food intake, and has abuse potential.

物理化学性质&存储条件

分子量	358.6899
分子式	C17H18Cl3NO
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	H2O: ≥ 52 mg/mL
Chemical Name/SMILES	Isoquinoline, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-7-methoxy-2-methyl-, hydrochloride (1:1)

参考文献

1. Keller HH, et al. Adv Biochem Psychopharmacol. 1982;31:249-63.

2. Tirelli E, et al. J Pharmacol Exp Ther. 1998 Jan;284(1):116-24.

Diclofensine hydrochloride (Ro 8-4650 hydrochloride)

生物&药学活性

物理化学性质&存储条件

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Diclofensine hydrochloride (Ro 8-4650 hydrochloride)

生物&药学活性

物理化学性质&存储条件

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