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首页-小分子抑制剂&激动剂-Antibiotics and Antivirals-HCV-Dichlorcyclizine
Dichlorcyclizine

Chemical Structure : Dichlorcyclizine

CAS No.: 1784701-16-1

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Dichlorcyclizine (DCCZ)

货号: PC-72892Not For Human Use, Lab Use Only.

Dichlorcyclizine (DCCZ) is a potent, small molecule HCV fusion inhibitor, also inhibits SARS-CoV and SARS-CoV-2 S-mediated infection with EC50 of 9.92 and 4.53 uM, respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Dichlorcyclizine (DCCZ) is a potent, small molecule HCV fusion inhibitor, also inhibits SARS-CoV and SARS-CoV-2 S-mediated infection in MA104 cells with EC50 of 9.92 and 4.53 uM, respectively.

    物理化学性质&存储条件

    分子量 349.299
    分子式 C19H22Cl2N2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    1-(bis(4-chlorophenyl)methyl)-4-ethylpiperazine

    参考文献

    1. Christopher D Ma, et al. Nat Microbiol. 2020 Dec;5(12):1532-1541.

    2. Park SB, et al. mBio. 2022 Jan 11;13(1):e0323821.

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