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首页-小分子抑制剂&激动剂-Others-Other Targets-Diacerein
Diacerein

Chemical Structure : Diacerein

CAS No.: 13739-02-1

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Diacerein (Diacerhein)

货号: PC-24030Not For Human Use, Lab Use Only.

Diacerein (Diacerhein) is an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling, also is a highly efficacious inhibitor of main protease (Mpro) of SARS-CoV-2, shows anti-inflammatory and anti-rheumatic effect.

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50 mg ￥480 In stock
100 mg ￥780 In stock
250 mg ￥1280 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Diacerein (Diacerhein) is an orally active anthraquinone, reduces production of IL-1 converting enzyme then inhibits the activation of IL-1β by related downstream signaling, also is a highly efficacious inhibitor of main protease (Mpro) of SARS-CoV-2, shows anti-inflammatory and anti-rheumatic effect.

物理化学性质&存储条件

分子量 368.30
分子式 C19H12O8
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

4,5-Diacetoxy-9,10-dioxo-9,10-dihydroanthracene-2-carboxylic acid

参考文献

1. Singh A, et al. Biochemistry. 2025 Jan 30. doi: 10.1021/acs.biochem.4c00535.

2. Birgit Lohberger, et al. BMC Cancer. 2015 Nov 10:15:891.

3. Shi S, et al. Front Pharmacol. 2020;11:560361.

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