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Dexrazoxane hydrochloride

Chemical Structure : Dexrazoxane hydrochloride

CAS No.: 149003-01-0

Dexrazoxane hydrochloride (ICRF-187 hydrochloride)

货号: PC-45965Not For Human Use, Lab Use Only.

A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals.

规格 价格 库存 数量
50 mg ¥760 In stock
100 mg ¥1040 In stock

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

A derivative of EDTA that chelates iron and reduces the number of metal ions complexed with anthracycline and, consequently, decrease the formation of superoxide radicals; protects the heart against the cardiotoxic side effects of chemotherapeutic drugs.

Chemotherapeutic Agents

Approved

物理化学性质&存储条件

分子量 304.7301
分子式 C11H17ClN4O4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1,3-Piperazinedione, 4,4'-[(1S)-1-methyl-1,2-ethanediyl]bis-, hydrochloride (1:?)

参考文献

1. Lipshultz SE, et al. N Engl J Med. 2004 Jul 8;351(2):145-53.

2. Bjelogrlic SK, et al. Exp Biol Med (Maywood). 2007 Dec;232(11):1414-24.

3. Jones RL, et al. Expert Rev Cardiovasc Ther. 2008 Nov;6(10):1311-7.

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