Deutivacaftor | CFTR potentiator | Probechem Biochemicals

Chemical Structure : Deutivacaftor

CAS No.: 1413431-07-8

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Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9, VX-770-d9)

货号: PC-23052Not For Human Use, Lab Use Only.

Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9) is a potent, orally active CFTR potentiator/modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE.

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10 mg	￥4580	In stock
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生物&药学活性

Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9) is a potent, orally active CFTR potentiator/modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE.

物理化学性质&存储条件

分子量	401.55
分子式	C24H19D9N2O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(2-(tert-butyl)-5-hydroxy-4-(2-(methyl-d3)propan-2-yl-1,1,1,3,3,3-d6)phenyl)-4-oxo-1,4-dihydroquinoline-3-carboxamide

参考文献

1. Uluer AZ, et al. Lancet Respir Med. 2023 Jun;11(6):550-562.

Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9, VX-770-d9)

生物&药学活性

物理化学性质&存储条件

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Deutivacaftor (VX-561, CTP-656, Ivacaftor-d9, VX-770-d9)

生物&药学活性

物理化学性质&存储条件

参考文献

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