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Des 1 inhibitor GT11

Chemical Structure : Des 1 inhibitor GT11

CAS No.: 649767-83-9

Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280)

货号: PC-26798Not For Human Use, Lab Use Only.

Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280) is a competitive inhibitor of dihydroceramide desaturase with Ki of 6 uM, induces Des1 inhibition in rat liver microsomes with IC50 of 20 uM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Des 1 inhibitor GT11 ((1R,2S)-Deoxy-PR280) is a competitive inhibitor of dihydroceramide desaturase with Ki of 6 uM, induces Des1 inhibition in rat liver microsomes with IC50 of 20 uM.

物理化学性质&存储条件

分子量 437.71
分子式 C27H51NO3
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-((1R,2S)-1,3-dihydroxy-1-(2-tridecylcycloprop-1-en-1-yl)propan-2-yl)octanamide

参考文献

1. G. Triola, et al. Mol. Pharmacol., 66 (2004), pp. 1671-1678.

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