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首页-抗体药物偶连体和PROTACs-Drug-Linker Conjugates-Deruxtecan
Deruxtecan

Chemical Structure : Deruxtecan

CAS No.: 1599440-13-7

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Deruxtecan (MC-GGFG-DXd)

货号: PC-28473Not For Human Use, Lab Use Only.

Deruxtecan (MC-GGFG-DXd) is an ADC drug-linker conjugate composed of DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing PROTAC Trastuzumab deruxtecan and Patritumab deruxtecan.

规格 价格 库存 数量
10 mg ￥880 In stock
25 mg ￥1380 In stock
50 mg ￥2280 In stock
100 mg Get quote
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

Deruxtecan (MC-GGFG-DXd) is an ADC drug-linker conjugate composed of DX-8951 derivative (DXd) and a maleimide-GGFG peptide linker, used for synthesizing PROTAC Trastuzumab deruxtecan and Patritumab deruxtecan.

物理化学性质&存储条件

分子量 1034.07
分子式 C52H56FN9O13
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-((S)-10-Benzyl-1-(((1S,9S)-9-ethyl-5-fluoro-9-hydroxy-4-methyl-10,13-dioxo-2,3,9,10,13,15-hexahydro-1H,12H-benzo[de]pyrano[3',4':6,7]indolizino[1,2-b]quinolin-1-yl)amino)-1,6,9,12,15-pentaoxo-3-oxa-5,8,11,14-tetraazahexadecan-16-yl)-6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanamide

参考文献

1. Ogitani Y, et al. Cancer Sci. 2016 Jul;107(7):1039-46.

2. NOGUCHI, Shigeru, et al. WO2017002776A1.

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