Delpazolid |CAS:1219707-39-7 Probechem Biochemicals

Chemical Structure : Delpazolid

CAS No.: 1219707-39-7

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Delpazolid (LCB01-0371;LCB 01-0371)

货号: PC-60037Not For Human Use, Lab Use Only.

Delpazolid (LCB01-0371) is an oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).

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10 mg	￥1280	In stock
25 mg	￥2180	In stock
50 mg	￥3580	In stock
100 mg		Get quote

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生物&药学活性

Delpazolid (LCB01-0371) is an oxazolidinone antibiotic that shows good antibacterial activity (MSSA MIC50=1 ug/mL).
Delpazolid (LCB01-0371) potently inhibits MSSA and MRSA clinical isolates with MIC of 0.5-2 and 0.5-4 ug/mL, respectively.
Delpazolid (LCB01-0371) shows more-potent protective effects (MSSA ED50=4.53 mg/kg) than Linezolid against systemic infections caused by Gram-positive and Gram-negative bacteria in mice model.

物理化学性质&存储条件

分子量	308.313
分子式	C14H17FN4O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(5R)-3-[3-fluoro-4-(1-methyl-5,6-dihydro-1,2,4-triazin-4(1H)-yl)phenyl]-5-(hydroxymethyl)-1,3-oxazolidin-2-one

参考文献

1. Jeong JW, et al. Antimicrob Agents Chemother. 2010 Dec;54(12):5359-62.

2. Kim TS, et al. Antimicrob Agents Chemother. 2017 Aug 24;61(9). pii: e02752-16.

3. Choi Y, et al. J Antimicrob Chemother. 2017 Oct 23. doi: 10.1093/jac/dkx367.

Delpazolid (LCB01-0371;LCB 01-0371)

生物&药学活性

物理化学性质&存储条件

参考文献

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Delpazolid (LCB01-0371;LCB 01-0371)

生物&药学活性

物理化学性质&存储条件

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