Delavirdine mesylate |CAS:147221-93-0 Probechem Biochemicals

Chemical Structure : Delavirdine mesylate

CAS No.: 147221-93-0

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Delavirdine mesylate (U 90152)

货号: PC-42659Not For Human Use, Lab Use Only.

A potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT.

规格	价格	库存
50 mg	￥560	In stock
100 mg	￥640	In stock
200 mg	￥1120	In stock

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生物&药学活性

A potent HIV-1 reverse transcriptase inhibitor with IC50 of 0.26 uM for recombinant HIV-1 RT; exhibits IC50>440 uM for DNA polymerases α and δ; blocks the replication in peripheral blood lymphocytes of 25 primary HIV-1 isolates and has low cellular cytotoxicity; retains significant activity against mutant RTs (K103N, Y181C).

HIV Infection

Approved

物理化学性质&存储条件

分子量	552.6668
分子式	C23H32N6O6S2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 40.3 mg/mL
Chemical Name/SMILES	Methanesulfonamide, N-[2-[[4-[3-[(1-methylethyl)amino]-2-pyridinyl]-1-piperazinyl]carbonyl]-1H-indol-5-yl]-, methanesulfonate (1:1)

参考文献

1. Dueweke TJ, et al. Antimicrob Agents Chemother. 1993 May;37(5):1127-31.

2. Romero DL, et al. J Med Chem. 1993 May 14;36(10):1505-8.

3. Olmsted RA, et al. J Virol. 1996 Jun;70(6):3698-705.

Delavirdine mesylate (U 90152)

生物&药学活性

物理化学性质&存储条件

参考文献

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Delavirdine mesylate (U 90152)

生物&药学活性

物理化学性质&存储条件

参考文献

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