Delamanid |CAS:681492-22-8 Probechem Biochemicals

Chemical Structure : Delamanid

CAS No.: 681492-22-8

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Delamanid (OPC67683;OPC-67683;OPC 67683)

货号: PC-42715Not For Human Use, Lab Use Only.

Delamanid (OPC-67683) is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB.

规格	价格	库存
25 mg	￥1980	In stock
50 mg	￥3280	In stock
100 mg	￥5280	In stock
200 mg		Get quote
1 g		Get quote

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生物&药学活性

Delamanid (OPC-67683) is a mycolic acid biosynthesis inhibitor found to be free of mutagenicity and to possess highly potent activity against tuberculosis, including MDR-TB.
Delamanid (OPC-67683) shows MIC of 0.006-0.024 ug/mL in vitro and highly effective therapeutic activity at low doses in vivo.

物理化学性质&存储条件

分子量	534.4844
分子式	C25H25F3N4O6
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 30 mg/mL
Chemical Name/SMILES	Imidazo[2,1-b]oxazole, 2,3-dihydro-2-methyl-6-nitro-2-[[4-[4-[4-(trifluoromethoxy)phenoxy]-1-piperidinyl]phenoxy]methyl]-, (2R)-

参考文献

1. Matsumoto M, et al. PLoS Med. 2006 Nov;3(11):e466.

2. Li X, et al. Bioorg Med Chem Lett. 2008 Apr 1;18(7):2256-62.

3. Hurdle JG, et al. J Antimicrob Chemother. 2008 Nov;62(5):1037-45.

Delamanid (OPC67683;OPC-67683;OPC 67683)

生物&药学活性

物理化学性质&存储条件

参考文献

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Delamanid (OPC67683;OPC-67683;OPC 67683)

生物&药学活性

物理化学性质&存储条件

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