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首页-小分子抑制剂&激动剂-Others-Human Antigen R (HuR)-Dehydromutactin
Dehydromutactin

Chemical Structure : Dehydromutactin

CAS No.: 823803-77-6

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Dehydromutactin

货号: PC-60908Not For Human Use, Lab Use Only.

Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM.

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Dehydromutactin is a small molecule inhibitor of RNA-binding protein Hu protein R (HuR) that interferes the HuR homodimerization with Kd of 40 nM.
    Dehydromutactin interferes with HuR RNA binding, HuR trafficking, cytokine expression and T-cell activation.
    Dehydromutactin is a valuable tool for studying HuR function.

    物理化学性质&存储条件

    分子量 284.267
    分子式 C16H12O5
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    6-(4,5-dihydroxy-2-methylnaphthalen-1-yl)-4-hydroxypyran-2-one

    参考文献

    1. Meisner NC, et al. Nat Chem Biol. 2007 Aug;3(8):508-15.

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