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首页-抗体和重组蛋白-Biosimilar Antibody-Daxdilimab
Daxdilimab

Chemical Structure : Daxdilimab

CAS No.: 2245966-28-1

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Daxdilimab (HZN-7734, VBI 7734)

货号: PC-38814Not For Human Use, Lab Use Only.

Daxdilimab (HZN-7734) is a fully human monoclonal antibody that binds to the ILT7 protein on the surface of plasmacytoid dendritic cells (pDCs) and recruits effector cells, such as natural killer (NK) cells, that help to kill pDCs.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

Daxdilimab (HZN-7734) is a fully human monoclonal antibody that binds to the ILT7 protein on the surface of plasmacytoid dendritic cells (pDCs) and recruits effector cells, such as natural killer (NK) cells, that help to kill pDCs.
ILT7 (CD85g, LILRA4) is a protein found specifically on pDCs, pDC depletion with daxdilimab prevents the production of type 1 interferons, pro-inflammatory cytokines.
Isotype: IgG1-lambda.
Anti-[human LILRA4 (leukocyte immunoglobulin like receptor A4, ILT7, CD85g)], human monoclonal antibody.

物理化学性质&存储条件

分子量
分子式
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

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