Dasotraline hydrochloride |CAS:675126-08-6 Probechem Biochemicals

Chemical Structure : Dasotraline hydrochloride

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Dasotraline hydrochloride (SEP 225289 hydrochloride;SEP-225289 hydrochloride;SEP225289 hydrochloride)

货号: PC-43257Not For Human Use, Lab Use Only.

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25 mg		Get quote
100 mg		Get quote
250 mg		Get quote
500 mg		Get quote

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生物&药学活性

Dasotraline (SEP-225289) is a novel triple reuptake inhibitor, antidepressant agent that blocks norepinephrine (NE), dopamine (DA) and serotonin (5-HT) transporters with IC50 values of 4, 6, and 11 nM, respectively; demonstrates potential for the treatment of attention-deficit/hyperactivity disorder (ADHD).

物理化学性质&存储条件

分子量	328.6639
分子式	C16H16Cl3N
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	DMSO: ≥ 31 mg/mL
Chemical Name/SMILES	1-Naphthalenamine, 4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydro-, hydrochloride (1:1), (1R,4S)-

参考文献

1. Koblan KS, et al. Neuropsychopharmacology. 2015 Nov;40(12):2745-52.

2. Hopkins SC, et al. Clin Drug Investig. 2016 Feb;36(2):137-46.

3. Guiard BP, et al. Int J Neuropsychopharmacol. 2011 Mar;14(2):211-23.

Dasotraline hydrochloride (SEP 225289 hydrochloride;SEP-225289 hydrochloride;SEP225289 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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Dasotraline hydrochloride (SEP 225289 hydrochloride;SEP-225289 hydrochloride;SEP225289 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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