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首页-小分子抑制剂&激动剂-Membrane Transporter/Ion Channel-iGluR-Dasolampanel
Dasolampanel

Chemical Structure : Dasolampanel

CAS No.: 503294-13-1

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Dasolampanel (NGX426)

货号: PC-61714Not For Human Use, Lab Use Only.

Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    Dasolampanel (NGX426) is an orally bioavailable, competitive antagonist of the AMPA-kainate receptors for the treatment of chronic pain conditions including neuropathic pain and migraine.

    物理化学性质&存储条件

    分子量 377.825
    分子式 C17H20ClN5O3
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    (3S,4aS,6S,8aR)-6-(3-chloro-2-(1H-tetrazol-5-yl)phenoxy)-decahydroisoquinoline-3-carboxylic acid

    参考文献

    1. Wallace MS, et al. Pain Med. 2012 Dec;13(12):1601-10.

    2. Martinez-Perez JA, et al. Bioorg Med Chem Lett. 2013 Dec 1;23(23):6463-6.

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