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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Aldose Reductase-Darirestat
Darirestat

Chemical Structure : Darirestat

CAS No.: 957051-88-6

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Darirestat (WJ-38)

货号: PC-22473Not For Human Use, Lab Use Only.

WJ-38 (Darirestat) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

WJ-38 (Darirestat) is a small molecule aldose reductase (AR) inhibitor, does not affect AR protein expression, reduces oxidative stress by activating the nuclear factor erythroid 2-related factor 2 (Nrf2) pathway.

物理化学性质&存储条件

分子量 392.23
分子式 C19H15Cl2NO4
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1(4H)-Quinolineacetic acid, 3-[(2,3-dichlorophenyl)methyl]-6-methoxy-4-oxo-

参考文献

1. Yang L, et al. Eur J Pharmacol. 2024 Mar 15;967:176376.

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