Dalosirvat (SM04554)

Chemical Structure : Dalosirvat

CAS No.: 1360540-81-3

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货号: PC-38354Not For Human Use, Lab Use Only.

Dalosirvat (SM04554) is a small-molecule Wnt pathway modulator, activates Wnt with IC50 of 28-29 nM, with potential topical treatment for androgenetic alopecia.

规格	价格	库存
10 mg	￥880	In stock
25 mg	￥1380	In stock
50 mg	￥2180	In stock
100 mg		Get quote

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生物&药学活性

Dalosirvat (SM04554) is a small-molecule Wnt pathway modulator, activates Wnt with IC50 of 28-29 nM, with potential topical treatment for androgenetic alopecia.
SM04554 increased total and nuclear β-catenin, versican and Ki-67 specifically in hair follicles.
SM04554 increased follicle numbers and hair growth.

物理化学性质&存储条件

分子量	296.322
分子式	C18H16O4
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-4-phenylbutane-1,4-dione

参考文献

1. V. Deshmukh, et al. DOI: https://doi.org/10.1016/j.jid.2017.02.735