Daidzin

Chemical Structure : Daidzin

CAS No.: 552-66-9

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货号: PC-27271Not For Human Use, Lab Use Only.

规格	价格	库存
25 mg	￥380	In stock
100 mg	￥780	In stock
250 mg	￥1280	In stock
1 g		Get quote

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生物&药学活性

Daidzin is a 7-glucoside of 4',7-dihydroxyisoflavone and a potent, selective, competitive inhibitor of human mitochondrial aldehyde dehydrogenase (ALDH-I, ALDH2) with Ki of 40 nM, >1000-fold selective over cytosolic aldehyde dehydrogenase isozyme (ALDH-II).
Daidzin does not inhibit human class I, II, or III alcohol dehydrogenases.
Daidzin can suppress ethanol intake of this species without blocking acetaldehyde metabolism.
Daidzin suppresses hamster ethanol intake also inhibit 5-HIAA and DOPAC formation.
Daidzin shows effective anti-inflammatory and antioxidant potential.

物理化学性质&存储条件

分子量	416.38
分子式	C21H20O9
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	3-(4-Hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

参考文献

1. Peterson G, et al. Biochem Biophys Res Commun. 1991 Aug 30;179(1):661-7.

2. Keung WM, et al. Proc Natl Acad Sci U S A. 1997 Mar 4;94(5):1675-9.

3. Keung WM, et al. Proc Natl Acad Sci U S A. 1996 Apr 30;93(9):4284-8.

4. Keung WM, et al. Proc Natl Acad Sci U S A. 1993 Feb 15;90(4):1247-51.

Daidzin

生物&药学活性

物理化学性质&存储条件

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Daidzin

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