欢迎访问ProbeChem中文网站，英文网站请访问www.probechem.com
    英文 |     中文

产品咨询: sales@probechem.com
订购: order@probechem.com

首页-小分子抑制剂&激动剂-Others-Other Targets-DX3-234
DX3-234

Chemical Structure : DX3-234

CAS No.:

加入收藏

DX3-234 (DX 3-234)

货号: PC-20780Not For Human Use, Lab Use Only.

DX3-234 is a potent selective complex I oxidative phosphorylation (OXPHOS) inhibitor with IC50 of 42.6 nM in NAD+/NADH assay and IC50 of 29 nM in ATP depletion assay using MIA PaCa-2 cells.

规格 价格 库存 数量
50 mg Get quote
100 mg Get quote
200 mg Get quote
1 g Get quote
获取报价单
* 请选择数量再加入购物车
 or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DX3-234 is a potent selective complex I oxidative phosphorylation (OXPHOS) inhibitor with IC50 of 42.6 nM in NAD+/NADH assay and IC50 of 29 nM in ATP depletion assay using MIA PaCa-2 cells.
DX3-234 inhibits the growth of MIA PaCa-2 cells with an IC50 value of 70 nM.
DX3-234 shows significant tumor suppression in the Pan02 syngeneic model of pancreatic cancer.

物理化学性质&存储条件

分子量 565.70
分子式 C25H35N5O6S2
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

O=C([C@H]1CN(S(=O)(C2=CC=C(S(=O)(C3CCC3)=O)C=C2)=O)CCC1)N4CCN(C5=NC(C(C)C)=NO5)CC4

参考文献

1. Ding Xue, et al. J Med Chem. 2022 Jan 13;65(1):343-368.

备案号：沪ICP备16042516号-1 Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright

联系我们 sales@probechem.com

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

  • *Product name:
  • *Applicant name:
  • *Email address:
  • *Organization name:
  • *Requested quantity:
  • *Country:
  • *Additional Information:

询单

  • *产品名称:
  • *姓名:
  • *邮箱:
  • *公司名称:
  • *询单数量:
  • *国籍:
  • 询单信息: