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首页-小分子抑制剂&激动剂-Metabolic Enzyme/Protease-Protein Phosphatase/PTP-DUSP6 inhibitor BCI
DUSP6 inhibitor BCI

Chemical Structure : DUSP6 inhibitor BCI

CAS No.: 1245792-51-1

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DUSP6 inhibitor BCI (NSC-150117, NSC150117)

货号: PC-60183Not For Human Use, Lab Use Only.

BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.

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5 mg ￥1280 In stock
10 mg ￥1880 In stock
25 mg ￥2980 In stock
50 mg ￥4880 In stock
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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

生物&药学活性

BCI (NSC150117) is a small-molecule, allosteric inhibitor of DUSP6 (dual-specificity phosphatase 6) with IC50 of 12.3 uM.
BCI (NSC150117) also inhibits human DUSP1 with IC50 of 11.5 uM.
BCI (NSC150117) suppresses the ERK-induced activation of Dusp6 and regulates heart size in zebrafish.

物理化学性质&存储条件

分子量 317.43
分子式 C22H23NO
外观性状 Solid
CAS No.
储存条件
固体粉末
-20 °C 12 个月; 4°C 6 个月
配置液
-80 °C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

(E)-2-benzylidene-3-(cyclohexylamino)-2,3-dihydro-1H-inden-1-one

参考文献

1. Molina G, et al. Nat Chem Biol. 2009 Sep;5(9):680-7.

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