DS88790512 |CAS: 2231089-95-3 Probechem Biochemicals

Chemical Structure : DS88790512

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DS88790512 (DS 88790512;DS-88790512)

货号: PC-35044Not For Human Use, Lab Use Only.

DS88790512 is a potent, selective, and orally bioavailable TRPC6 blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).

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DS88790512 is a potent, selective, and orally bioavailable TRPC6 blocker with IC50 of 11 nM, exhibits excellent selectivity against hERG and hNaV1.5 channels (IC50 >100 uM).

物理化学性质&存储条件

分子量	367.493
分子式	C22H29N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4-(((1R,3aR,7aS)-2-((R)-3-aminopiperidin-1-yl)-7a-methyl-5-oxooctahydro-1H-inden-1-yl)oxy)benzonitrile

参考文献

1. Motoyama K, et al. Bioorg Med Chem Lett. 2018 Mar 22. pii: S0960-894X(18)30251-8.

DS88790512 (DS 88790512;DS-88790512)

生物&药学活性

物理化学性质&存储条件

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DS88790512 (DS 88790512;DS-88790512)

生物&药学活性

物理化学性质&存储条件

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