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首页-小分子抑制剂&激动剂-Epigenetics-Histone Methyltransferase (HMTase)-DS79932728
DS79932728

Chemical Structure : DS79932728

CAS No.: 2757191-62-9

DS79932728 (DS 79932728)

货号: PC-23812Not For Human Use, Lab Use Only.

DS79932728 is a potent and orally bioavailable histone lysine methyltransferase EHMT2/1 (G9a/GLP) inhibitor with IC50 of 12.6/75.7 nM respectively.

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纯度 & COA & 质检文件 纯度: >98% (HPLC)

生物&药学活性

DS79932728 is a potent and orally bioavailable histone lysine methyltransferase EHMT2/1 (G9a/GLP) inhibitor with IC50 of 12.6/75.7 nM respectively.

物理化学性质&存储条件

分子量 311.43
分子式 C19H25N3O
外观性状 Solid
CAS No.
储存条件
固体粉末
-20°C 12 个月; 4°C 6 个月
配置液
-80°C 6 个月; -20°C 6 个月
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

5'-methoxy-6'-(1-methyl-2,5,6,7-tetrahydro-1H-azepin-4-yl)spiro[cyclobutane-1,3'-indol]-2'-amine

参考文献

1. Katayama K, et al. ACS Med Chem Lett. 2020 Dec 28;12(1):121-128.

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