DS79182026 | Hepcidin inhibitor | Probechem Biochemicals

Chemical Structure : DS79182026

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DS79182026 (DS 79182026, DS-79182026)

货号: PC-61013Not For Human Use, Lab Use Only.

DS79182026 (DS-79182026) is a potent, orally active hepcidin production inhibitor with IC50 of 39 nM, with low kinase inhibitory activity.

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生物&药学活性

DS79182026 (DS-79182026) is a potent, orally active hepcidin production inhibitor with IC50 of 39 nM, with low kinase inhibitory activity.
DS79182026 inhibits hepcidin production in HepG2 cell, slowers serum hepcidin in mouse IL-6 induced acute inflammatory model.

物理化学性质&存储条件

分子量	349.35
分子式	C18H15N5O3
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	methyl (6-(5-methyl-3-(pyridin-2-yl)-1H-pyrazol-4-yl)benzo[d]isoxazol-3-yl)carbamate

参考文献

1. Fukuda T, et al. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3716-3722.

DS79182026 (DS 79182026, DS-79182026)

生物&药学活性

物理化学性质&存储条件

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DS79182026 (DS 79182026, DS-79182026)

生物&药学活性

物理化学性质&存储条件

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