DS0464 | SARS-CoV-2 nsp14 inhibitor | Probechem Biochemicals

Chemical Structure : DS0464

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DS0464 (DS-0464, DS 0464)

货号: PC-72806Not For Human Use, Lab Use Only.

DS0464 is a selective, bisubstrate competitive inhibitor SARS-CoV-2 nonstructural protein 14 (nsp14) with IC50 of 1.1 uM, also selective against 28 out of 33 RNA, DNA, and protein MTases.

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生物&药学活性

DS0464 is a selective, bisubstrate competitive inhibitor SARS-CoV-2 nonstructural protein 14 (nsp14) with IC50 of 1.1 uM, also selective against 28 out of 33 RNA, DNA, and protein MTases.

物理化学性质&存储条件

分子量	473.552
分子式	C21H27N7O4S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(2-((((2S,3S,4R)-5-(6-amino-9H-purin-9-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl)thio)ethyl)-3-phenethylurea

参考文献

1. Kanchan Devkota, et al. SLAS Discov. 2021 Oct;26(9):1200-1211.

2. Devkota K, et al. bioRxiv. 2021 Feb 19:2021.02.19.424337.

DS0464 (DS-0464, DS 0464)

生物&药学活性

物理化学性质&存储条件

参考文献

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DS0464 (DS-0464, DS 0464)

生物&药学活性

物理化学性质&存储条件

参考文献

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