DS-5272 |CAS:1235575-97-9 Probechem Biochemicals

Chemical Structure : DS-5272

加入收藏

DS-5272 (DS 5272;DS5272)

货号: PC-60481Not For Human Use, Lab Use Only.

DS-5272 is a potent and orally active p53-MDM2 interaction inhibitor with IC50 of 2.4 nM.

规格	价格	库存	数量
25 mg		Get quote
50 mg		Get quote
100 mg		Get quote
250 mg		Get quote

获取报价单

* 请选择数量再加入购物车

or Bulk Inquiry

大包装，大折扣！

E-mail: sales@probechem.com

Tech Support: tech@probechem.com

生物&药学活性

DS-5272 is a potent and orally active p53-MDM2 interaction inhibitor with IC50 of 2.4 nM.
DS-5272 inhibits SJSA-1 cell proliferation with GI50 of 0.17 uM, demonstrates excellent antitumor efficacy on SJSA-1 xenografted models with high safety and good PK profiles.

物理化学性质&存储条件

分子量	703.675
分子式	C34H38Cl2F2N6O2S
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	((5R,6S)-5-(4-chloro-3-fluorophenyl)-6-(6-chloropyridin-3-yl)-3-isopropyl-6-methyl-5,6-dihydroimidazo[2,1-b]thiazol-2-yl)((2S,4R)-2-((R)-6-ethyl-4,7-diazaspiro[2.5]octane-7-carbonyl)-4-fluoropyrrolidin-1-yl)methanone

参考文献

1. Miyazaki M, et al. Bioorg Med Chem. 2015 May 15;23(10):2360-7.

DS-5272 (DS 5272;DS5272)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

DS-5272 (DS 5272;DS5272)

生物&药学活性

物理化学性质&存储条件

参考文献

Bulk Inquiry

* Indicates a Required FieldYour information is safe with us.

询单

Get Quotation Now

* Indicates a Required FieldYour information is safe with us.