DS-1040 | TAFIa inhibitor | Probechem Biochemicals

Chemical Structure : DS-1040

CAS No.: 1335138-62-9

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DS-1040 (DS 1040, DS1040)

货号: PC-61009Not For Human Use, Lab Use Only.

DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.

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5 mg	￥1580	In stock
10 mg	￥2480	In stock
25 mg	￥4280	In stock
50 mg	￥7280	In stock
100 mg		Get quote

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生物&药学活性

DS-1040 (DS1040) is a small molecule inhibitor of the activated thrombin-activatable fibrinolysis inhibitor (TAFIa) with IC50 of 1.7 ng/mL for rabbit TAFIa.
DS-1040 is a novel fibrinolysis-enhancing agent has favorable pharmacokinetic/pharmacodynamic properties and a favorable safety profile.

物理化学性质&存储条件

分子量	293.411
分子式	C16H27N3O2
外观性状	Solid
CAS No.
储存条件	固体粉末 -20 °C 12 个月; 4°C 6 个月	配置液 -80 °C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(2S)-5-Amino-2-[[1-(trans-4-methylcyclohexyl)-1H-imidazol-4-yl]methyl]valeric acid

参考文献

1. Zhou J, et al. J Thromb Haemost. 2017 May;15(5):961-971.

2. Gurewich V, et al. J Thromb Haemost. 2017 Oct;15(10):2080-2081.

3. Paul A Lapchak, et al. Abstract WP282: DS-1040 an Inhibitor of the Activated Thrombin Activatable Fibrinolysis Inhibitor Improves Behavior in Embolized Rabbits, Stroke. 2016;47:AWP282.

DS-1040 (DS 1040, DS1040)

生物&药学活性

物理化学性质&存储条件

参考文献

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DS-1040 (DS 1040, DS1040)

生物&药学活性

物理化学性质&存储条件

参考文献

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