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DRP1 inhibitor 4

Chemical Structure : DRP1 inhibitor 4

CAS No.: 2225902-98-5

DRP1 inhibitor 4

货号: PC-35265Not For Human Use, Lab Use Only.

DRP1 inhibitor 4 is a selective, small molecule inhibitor of the mammalian mitochondrial division dynamin, DRP1 with IC50 of 1.0 uM, shows no activity against OPA1 and DYN1 (IC50>100 uM)..

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DRP1 inhibitor 4 is a selective, small molecule inhibitor of the mammalian mitochondrial division dynamin, DRP1 with IC50 of 1.0 uM, shows no activity against OPA1 and DYN1 (IC50>100 uM).

    物理化学性质&存储条件

    分子量 448.549
    分子式 C22H24N8OS
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20 °C 12 个月; 4°C 6 个月
    配置液
    -80 °C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    N-(4-(1H-tetrazol-5-yl)phenyl)-4-methyl-1-((2-(piperidin-1-yl)thiazol-4-yl)methyl)-1H-pyrrole-2-carboxamide

    参考文献

    1. Mallat A, et al. Biochem Biophys Res Commun. 2018 May 15;499(3):556-562.

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