DR4004 hydrochloride | 5-HT7 antagonist | Probechem Biochemicals

Chemical Structure : DR4004 hydrochloride

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DR4004 hydrochloride (DR-4004 hydrochloride)

货号: PC-22275Not For Human Use, Lab Use Only.

DR4004 (DR-4004) hydrochloride is a potent, highly selective 5-HT7 antagonist with bingding pKi of 8.67, >50-fold selectivity over the 5-HT2 receptor, and other 5-HT receptors.

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生物&药学活性

DR4004 (DR-4004) hydrochloride is a potent, highly selective 5-HT7 antagonist with bingding pKi of 8.67, >50-fold selectivity over the 5-HT2 receptor, and other 5-HT receptors.

物理化学性质&存储条件

分子量	423.00
分子式	C26H31ClN2O
外观性状	Solid
CAS No.
储存条件	固体粉末 -20°C 12 个月; 4°C 6 个月	配置液 -80°C 6 个月; -20°C 6 个月
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benz[cd]indol-2(1H)-one, 2a-[4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl]-2a,3,4,5-tetrahydro-, hydrochloride (1:1)

参考文献

1. Ehlen JC, et al. J Neurosci. 2001 Jul 15;21(14):5351-7.

2. Kogan HA, et al. Eur J Pharmacol. 2002 Aug 2;449(1-2):105-11.

3. Chika Kikuchi, et al. J. Med. Chem. 1999, 42, 4, 533–535.

DR4004 hydrochloride (DR-4004 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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DR4004 hydrochloride (DR-4004 hydrochloride)

生物&药学活性

物理化学性质&存储条件

参考文献

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