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首页-小分子抑制剂&激动剂-GPCR-Opioid Receptor-DPI-287
DPI-287

Chemical Structure : DPI-287

CAS No.: 519058-13-0

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DPI-287 (DPI 287)

货号: PC-49552Not For Human Use, Lab Use Only.

DPI-287 is a small-molecule agonist of the δ-opioid receptor (DOP, DOR) with Ki vaule of 0.39 nM, shows 10-fold selectivity for DOP over MOP (Ki=3.17 nM).

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纯度 & COA & 质检文件 纯度: >98% (HPLC) Select Batch:

    生物&药学活性

    DPI-287 is a small-molecule agonist of the δ-opioid receptor (DOP, DOR) with Ki vaule of 0.39 nM, shows 10-fold selectivity for DOP over MOP (Ki=3.17 nM).

    物理化学性质&存储条件

    分子量 485.67
    分子式 C31H39N3O2
    外观性状 Solid
    CAS No.
    储存条件
    固体粉末
    -20°C 12 个月; 4°C 6 个月
    配置液
    -80°C 6 个月; -20°C 6 个月
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    4-((R)-((2S,5R)-4-benzyl-2,5-dimethylpiperazin-1-yl)(3-hydroxyphenyl)methyl)-N,N-diethylbenzamide

    参考文献

    1. Tobias Claff, et al. Sci Adv. 2019 Nov 27;5(11):eaax9115.

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